When I went to school in the 20th century, “quantum measurements” in the laboratory were typically performed on ensembles of similarly prepared systems. In the 21st century, it is becoming increasingly routine to perform quantum measurements on single atoms, photons, electrons, or phonons. The 2012 Nobel Prize in Physics recognizes two of the heros who led these revolutionary advances, Serge Haroche and Dave Wineland. Good summaries of their outstanding achievements can be found at the Nobel Prize site, and at Physics Today.
Serge Haroche developed cavity quantum electrodynamics in the microwave regime. Among other impressive accomplishments, his group has performed “nondemolition” measurements of the number of photons stored in a cavity (that is, the photons can be counted without any of the photons being absorbed). The measurement is done by preparing a Rubidium atom in a superposition of two quantum states. As the Rb atom traverses the cavity, the energy splitting of these two states is slightly perturbed by the cavity’s quantized electromagnetic field, resulting in a detectable phase shift that depends on the number of photons present. (Caltech’s Jeff Kimble, the Director of IQIM, has pioneered the development of analogous capabilities for optical photons.)
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Quantum Frontiers 